B12

Contents Mecobalamin Form / storage Typically a solution — store refrigerated (2–8 °C), protect from light (cobalamins are highly light-sensitive). Powder form: store at −20 °C, protect from light. Purity ≥98% — see lot COA CAS 13422-55-4 Molecular formula C63H91CoN13O14P Molecular weight ~1344.4 g/mol Sizes 10 mL (solution) Testing Identity (UV/Vis λmax), purity, assay (Beer-Lambert), heavy metals, microbial (TAMC/TYMC) COA Batch-specific — view on this page Research background Methylcobalamin is a biologically active form of vitamin B12, distinguished from cyanocobalamin by a methyl group bound to the central cobalt in place of a cyano group. It is a corrin-ring coordination complex and is highly light-sensitive. As a cofactor it participates in methyl-transfer reactions, notably the methionine-synthase pathway central to one-carbon and homocysteine metabolism, and is used as a reference standard in methylation chemistry and B12-dependent enzymology. Research applications Reference cofactor in methylation / one-carbon-metabolism studies B12-dependent enzyme (methionine synthase) research Neuronal cell-culture and homocysteine-pathway studies Quality & documentation Every lot is tested by an independent third-party laboratory before it enters the catalog.