LOT YPB.200✓ COA VERIFIED
✓ Purity ≥ 98%Research use only
GLP-1 S
Vial size
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Certificate of Analysis — Lot YPB.200
View COACompound information
Molecular profile
What is GLP-1 S?
Reference data for this compound is being added. Every lot still ships with its third-party Certificate of Analysis.
Storage requirements
Stability information
Protect from lightRoom-temp stable (short-term)
Lyophilized (powder)−20°C · stable long-term
Reconstituted2–8°C · use within 30 days
Lab verification
Verified by a third-party lab
This lotYPB.200
TestedDec 2025 · USA
Result6 of 6 tests passed
Research overview
GLP-1 S in the literature
Contents Semaglutide Form / storage Lyophilized powder; store at −20 °C, protect from light Purity ≥98% — see lot COA CAS 910463-68-2 Molecular formula C187H291N45O59 Molecular weight 4113.58 g/mol Sizes 10 mg / 20 mg / 30 mg Testing Identity (UV/Vis λmax), purity, assay (Beer-Lambert), heavy metals, microbial (TAMC/TYMC) COA Batch-specific — view on this page Research background Semaglutide is a synthetic analog of human glucagon-like peptide-1 (GLP-1) in which an Aib substitution at position 2 and a C18 fatty-diacid chain (linked via glutamate/AEEA to Lys20) confer resistance to DPP-4 cleavage and promote albumin binding, substantially extending circulating half-life relative to native GLP-1. Mechanistically it is studied as a selective agonist at the GLP-1 receptor, a class B G-protein-coupled receptor. In preclinical and in vitro models it is investigated for effects on glucose-dependent insulin secretion, beta-cell signaling, gastric-emptying physiology, and central appetite-regulating pathways, and it serves as a standard comparator in incretin pharmacology and next-generation receptor-agonist research.
HighlightsIn preclinical and in vitro models it is investigated for effects on glucose-dependent insulin secretion, beta-cell signaling, gastric-emptying physiology, and central appetite-regulating pathways, and it serves as a standard comparator in incretin pharmacology and next-generation receptor-agonist research.Research applications Reference agonist in GLP-1 receptor binding and cAMP signaling assays Preclinical models of energy balance and glucose homeostasis Comparator in structure-activity studies of acylated peptide analogs Quality & documentation Every lot is tested by an independent third-party laboratory before it enters the catalog.Testing covers identity (characteristic UV/Vis λmax matched to a reference standard), percent purity (≥98%, correlation-coefficient method), quantitative assay (Beer-Lambert, ≥95% of label claim), heavy metals (total ≤150 ppb — Pb, Cd, Hg, Ni, Fe, Co), and microbial limits (TAMC/TYMC).Each order ships with the Certificate of Analysis matching its lot number.
COA breakdown
✓ 6 of 6 tests passedPASSIdentityλ-max matchesLambda-max vs reference standardPASSPurity≥98% · UV/VisUV/Vis correlationPASSQuantitative assay≥95% of labelBeer-Lambert · ≥95% label claimPASSHeavy metals<20 ppbNMT 150 ppb/vial specPASSTAMC · aerobic microbial0 CFUNMT 1,000 CFU · 48 h @ 37 °CPASSTYMC · yeast & mold0 CFUNMT 100 CFU · 48 h @ 30 °C
Purity is measured per lot; panel results per the Analytical Formulations summary report for the lot currently shipping.
Product details
- Type
- Research peptide
- Form
- Lyophilized powder
- Storage
- Room temp in transit · −20 °C long-term
