
Contents ACTH(4-7)-PGP Form / storage Lyophilized powder; store at −20 °C, protect from light Purity ≥98% — see lot COA CAS 80714-61-0 (free base) Molecular formula C37H51N9O10S Molecular weight 813.9 g/mol Sizes 10 mg Testing Identity (UV/Vis λmax), purity, assay (Beer-Lambert), heavy metals, microbial (TAMC/TYMC) COA Batch-specific — view on this page Research background Semax pairs the ACTH(4-7) core (Met-Glu-His-Phe — lacking the corticotropic activity of full ACTH) with a C-terminal Pro-Gly-Pro extension for metabolic stability. Mechanisms studied in laboratory and animal research include upregulation of BDNF and NGF and their receptors, modulation of dopaminergic and serotonergic transmission, and antihypoxic/neuroprotective activity. Areas of interest include cognition and attention, neuroprotection in cerebral-ischemia models, and neural recovery; much published evidence is preclinical or from Russian-language clinical studies. Research applications Preclinical cognition and neuroprotection research Neurotrophic-factor (BDNF, NGF) expression studies Ischemia/hypoxia and neuroinflammation research Quality & documentation Every lot is tested by an independent third-party laboratory before it enters the catalog.
Purity is measured per lot; panel results per the Analytical Formulations summary report for the lot currently shipping.