
Contents GRF(1-29)NH₂ Form / storage Lyophilized powder; store at −20 °C, protect from light Purity ≥98% — see lot COA CAS 86168-78-7 (free base); 114466-38-5 (acetate) Molecular formula C149H246N44O42S Molecular weight 3357.9 g/mol (free base) Testing Identity (UV/Vis λmax), purity, assay (Beer-Lambert), heavy metals, microbial (TAMC/TYMC) COA Batch-specific — view on this page Research background Sermorelin corresponds to the biologically active N-terminal 1-29 segment of human growth-hormone-releasing hormone. In experimental systems it binds the GHRH receptor on pituitary somatotrophs and is studied as a model agonist that triggers cAMP signaling and pulsatile GH release, reproducing GHRH activity with a shorter, tractable sequence. Investigators use it to probe the architecture and regulation of the GHRH/GH/IGF-1 axis, to characterize receptor pharmacology, and as a comparator in studies of longer-acting GHRH analogs. Research applications Reference agonist in GHRH-receptor binding and signaling assays Probe for somatotroph physiology and GH secretory dynamics Comparator in stability/structure-activity studies of GHRH analogs Quality & documentation Every lot is tested by an independent third-party laboratory before it enters the catalog.
Purity is measured per lot; panel results per the Analytical Formulations summary report for the lot currently shipping.