LYSINE-PROLINE-VALINE

Contents KPV Form / storage Lyophilized powder; store at −20 °C, protect from light Purity ≥98% — see lot COA CAS 67727-97-3 Molecular formula C16H30N4O4 Molecular weight 342.43 g/mol Testing Identity (UV/Vis λmax), purity, assay (Beer-Lambert), heavy metals, microbial (TAMC/TYMC) COA Batch-specific — view on this page Research background KPV corresponds to the C-terminal (11-13) sequence of alpha-melanocyte-stimulating hormone. Despite its small size it appears to retain anti-inflammatory signaling associated with the parent hormone while lacking pigmentary effects; studies have examined its cellular uptake and proposed influence on pro-inflammatory transcription pathways such as NF-κB. In the preclinical literature it has been investigated in models of mucosal and intestinal inflammation, and is commonly used as a research tool for small-peptide modulation of inflammatory responses. Research applications Preclinical models of intestinal/mucosal inflammation NF-κB and pro-inflammatory cytokine signaling studies Reference for α-MSH-derived peptide activity Quality & documentation Every lot is tested by an independent third-party laboratory before it enters the catalog.